i installed roxio 10 the other day been going fine then went to open it up by hitting the shortcut on desktop and it wont open so i tried the one in all programs still no good , so far tried all and still no luck what is going on.
i got vista ultimate.

Your Norton, McAfee, or other registry cleaner killed the program. Read this:

http://forums.support.roxio.com/index.php?showtopic=37162

thanks for reply mate as all fixed by installing again just hope they do a fix soon then , just have to remember not to run a reg clean lol.

There is a fix linked to that post now. If you use a registry cleaner and break it again, try the fix.