I am getting the same error as Wussery did but I am running Windows 7 Ultimate 64 bit. Error is "All Your Drives are Set to Disabled. On this Operating System, in order to start Creator Premier you must either physically remove your drive(s) or enable at least one drive." I have disabled the drive then re-enabled it. I have tried to reinstall Roxio Creator Premier 10. I have uninstalled IE 9 Beta, a good move even without the above problem. I continue to get the same error message. This program worked at one point on this computer and it was purchased with the computer. Any other ideas on how to fix the problem would be appreciated.